A pioneering study has shown that a simple invertebrate, larvae of the wax moth Galleria mellonella, can be used as a novel infection model for bacteria from the Mycobacterium tuberculosis complex.
We have recently committed £2.4m to seven new project grants, awarded to outstanding projects from a broad range of scientific disciplines.
Today the NC3Rs is launching a series of checklists that will support UK funding bodies to ensure animal research carried out overseas is conducted to appropriate standards of welfare.
The 2018 CRACK IT Challenges are now live. This year's competition consists of three Challenges identified jointly by the NC3Rs and Sponsors.
We recently sponsored three events as part of the worldwide Pint of Science festival, which brings researchers into local pubs every May to talk about their work.
Adequate reporting is crucial for the transparency and reproducibility of preclinical research, including studies that use animals.
The British Pharmacological Society (BPS) and partner organisations have launched a new curriculum for undergraduate and taught Masters education on the use of research animals. The NC3Rs is pleased to be supporting this cross-sector initiative.
Three awards totalling £219,339 have been made in the 2018 NC3Rs Skills and Knowledge Transfer funding competition.
Today, AstraZeneca has signed a strategic agreement with Emulate, a leading Organ-Chip company, to accelerate the application of these technologies in their drug discovery programmes.
Launching today, the NC3Rs Gateway is a new publication portal on the F1000Research publication platform dedicated to the 3Rs, featuring methodology articles, reviews and source data that describe in detail how the use of animals in research can be
In February 2018, Dr María Duque-Correa, a David Sainsbury Fellow based at the Wellcome Sanger Institute, visited Colombia with a special mission: to ‘hunt’ the parasitic whipworm.
The NC3Rs is once again sponsoring public engagement events around the UK as part of this year's Pint of Science festival.
Work on an in silico model that predicts cardiotoxicity more accurately than animal studies has won the 2017 3Rs Prize, awarded by the NC3Rs and sponsored by GSK.
To celebrate International Women’s Day 2018, we are highlighting a number of female researchers at different career stages, including NC3Rs grant holders, whose fantastic work across a broad range of disciplines is helping advance the 3Rs in the UK
The NC3Rs has provided a peer review and advice service to the major UK funders of animal research for over a decade.
Seven teams have been awarded funding in the 2017 CRACK IT Challenge competition, which brings together industry, academia and SMEs to develop marketable products or improve business processes that will have a significant 3Rs impact.
Researchers at Newcastle University have found that picking up laboratory mice by the tail makes them less responsive to reward, suggesting a more depressive-like state compared to mice handled using a tunnel1. This finding adds to previous studies
In late 2016 the NC3Rs recruited two Regional Programme Managers, Dr Kamar Ameen-Ali and Dr Emma Stringer.
We are pleased to announce four new NC3Rs Fellowships, a commitment of just over £730,000, awarded to support 3Rs research in a range of disease areas.
Researchers from the Universities of Birmingham and Oxford, funded by the NC3Rs, have developed a new self-structuring model of bone tissue in vitro that can be used instead of experiments on live animals to study bone formation and maturation