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Our Project grant scheme is open for applications, supporting the development of new 3Rs approaches and technologies!

NC3Rs: National Centre for the Replacement Refinement & Reduction of Animals in Research

Latest News

Keep up to date with the latest news from the NC3Rs, including the researchers we fund. Follow us on social media and subscribe to our newsletter to get the latest updates directly.

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We are pleased to announce that Professor Paul Evans, Professor Christopher George, Ms Linda Horan, Professor Nick Plant and Dr Sally Robinson have joined the NC3Rs Board.

Word cloud of keywords related to the NC3Rs Board (e.g. 3Rs, science, funding)

We have published a new review of our CRACK IT programme. In it, we reflect on the first eight years of CRACK IT and how it has achieved business, scientific and 3Rs impacts through open innovation and collaboration.

Publication of the CRACK IT Review 2019

A new paper published in Scientific Reports describes the Fish Behaviour Index (FBI), an automated tool to monitor the behaviour of singly housed zebrafish, developed by NC3Rs grant holder Dr Lynne Sneddon and colleagues at the University of

Headshot of a zebrafish

Last month we sponsored three events as part of Pint of Science, an annual festival that invites researchers into pubs and cafes around the world to speak to the public about what they do.

The 3R's pamphlet with the Pint of Science advertisement board in the background

In this guest blog post, Dr Sally Robinson, Director of Animal Sciences and Technologies at AstraZeneca (Alderley Park), explores how the company has implemented the single use of needles as a refinement across their sites.


We have made eight awards totalling £585k in the 2019 Skills and Knowledge Transfer funding competition, which facilitates the exchange of models, tools or technologies with proven 3Rs potential between laboratories and institutions.

 Cancer Research UK and NC3Rs logo

Our new Innovation Platform website is now live. As well as showcasing projects funded through our CRACK IT programme, the Innovation Platform will connect researchers across sectors and disciplines to accelerate the development, application and

Screenshot of the CRACK IT Innovation Platform website

Next month offers a chance to hear about exciting 3Rs research first hand, as we take part in Pint of Science, a worldwide science festival that brings researchers to your local pub to present their scientific discoveries.

Pint of science logo

We are hosting a Twitter chat on Tuesday 5 March from 2pm to 4pm (GMT), which will give you a chance to ask questions about refined mouse handling methods and discuss your experiences.

A brown mouse in a tube

Four new NC3Rs Training Fellowships, totalling £460k, have been awarded to talented 3Rs-minded postdoctoral researchers to support the development of their careers.

A laboratory technician working with a microscope