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Use the filters below to identify NC3Rs projects relevant to your work by R, topic, model or activity type. If you are looking for something specific, you can add keyword(s) into the search box.

Activity type

Topic

Model

Impact stories

673 results

Identifying more clinically effective analgesic regimens and potential strain differences in pain perception in mice using a novel Operant Pain Assay

Principal Investigator: Dr Matt Leach, Newcastle University

Project grant

Side shot of Dr Matt Leach on a laptop and a monitor beside it

Identifying regulators of tissue regeneration by in vivo imaging in the zebrafish

Principal Investigator: Dr Robert Knight, King's College London

PhD Studentship

RespiraTox: In silico model for predicting human respiratory irritation

Contractor: Dr Sylvia Escher, Fraunhofer ITEM

CRACK IT Challenge

A chicken primary B cell culture model to study the pathogenesis and improve the control of immunosuppressive viruses of poultry

Principal Investigator: Dr Andrew Broadbent, The Pirbright Institute

Project grant

Ex vivo model for the study of epicardium-targeted therapies

Principal Investigator: Dr Paola Campagnolo, University of Surrey

Project grant

Dr Paola Campagnolo on the left with three colleagues on the right side of her in a laboratory

A comprehensive in silico approach to measure spatio-temporal changes of bone tissue in mouse models of osteoporosis and osteoarthritis

Principal Investigator: Dr Enrico Dall'Ara, University of Sheffield

Project grant

Quantifying the potential of skin swabbing as a refinement for DNA sampling of laboratory fish

Principal Investigator: Dr Will Norton, University of Leicester

Project grant

a zebrafish is held in a hand net and swabbed.

Intestinal organoids as a replacement strategy to unravel early host intestinal epithelia interactions with whipworms

Principal Investigator: Dr Maria Duque Correa, Wellcome Trust Sanger Institute

Fellowship

Developing human organotypic perfused bioreactors for physiologically reproducible therapeutic compound screening of a tumour microenvironment

Principal Investigator: Dr Xiao Wan, University of Oxford

Fellowship

A technique to test novel methods of controlling poultry red mite in hens without performing field-scale trials

Principal Investigator: Dr Alasdair Nisbet, Moredun Research Institute

Project grant

The use of PrP transgenic Drosophila to replace and reduce mice in the bioassay of mammalian prions

Principal Investigator: Dr Raymond Bujdoso, University of Cambridge

Partnerships and impact awards

Validating the cross-species comparative in silico platform (CRISP)

Contractor: Dr Will Krawszik, Moleculomics

CRACK IT Solution

Development, validation and application of enhanced-welfare technology for wild small mammal research

Principal Investigator: Dr Sarah Knowles, University of Oxford

Project grant

In silico design and optimisation of novel host-directed therapies

Principal Investigator: Dr Reiko Tanaka, Imperial College London

PhD Studentship

Organoid and single cell models of bladder cancer

Principal Investigator: Professor Margaret Knowles, University of Leeds

PhD Studentship

In vitro reconstitution of the polymicrobial community associated with cystic fibrosis airway infections

Principal Investigator: Dr Martin Welch, University of Cambridge

PhD Studentship

Replacing liver cancer models by modeling human liver cancer in vitro

Principal Investigator: Dr Meritxell Huch, University of Cambridge

Project grant

Reducing the animal cost of CRISPR/Cas9 mutagenesis

Principal Investigator: Dr Ben Davies, University of Oxford

Project grant

Development of a biologically-relevant preclinical radiotherapy dosimetry phantom

Principal Investigator: Professor Karen Kirkby, University of Manchester

PhD Studentship

Investigation of key inflammatory cells & mediators in zebrafish larval tailfin & heart repair/regeneration following resolution of inflammation

Principal Investigator: Professor Adriano Rossi, University of Edinburgh

PhD Studentship