Maternal immune activation: advancing from rodents to humans through a development of a hIPSC model to study gene x environment interactions Principal Investigator: Dr Anthony Vernon, King's College London PhD Studentship
Development of novel models of kidney damage using induced human pluripotent stem cells Principal Investigator: Dr Derek Brazil, Queen's University Belfast PhD Studentship
Fusogenic liposomes: the innovative delivery of compounds into human platelets to reduce animal use in platelet research Principal Investigator: Dr Alice Pollitt, University of Reading PhD Studentship
Replacement of animal models of cardiac arrest and resuscitation strategies using a computer simulation Principal Investigator: Professor Jonathan Hardman, University of Nottingham PhD Studentship
Replacing Alzheimer's disease (AD) - Down syndrome (DS) mice with fly models Principal Investigator: Dr Frances Wiseman, University College London PhD Studentship
Towards multiplexed in vivo phenotypic screening to improve antimicrobial drug discovery Principal Investigator: Dr Matthew Child, Imperial College London PhD Studentship
Implementation of a 3D Computational Mouse Atlas for Detection of Pancreatic Tumours in Transgenic Mice Principal Investigator: Dr Algernon Bloom, Queen Mary University of London Partnerships and impact awards
Fully humanised 3D vascular perfused model for breast cancer modelling and therapeutic screening Principal Investigator: Professor Valerie Speirs, University of Aberdeen Partnerships and impact awards
Galleria mellonella as an infection model for viral pathogens Principal Investigator: Professor Richard Titball, University of Exeter Project grant
Experimental evolution of Pseudomonas aeruginosa in media replicating the conditions of the upper and lower airways Principal Investigator: Dr Daniel Neill, University of Liverpool PhD Studentship
Reducing number of mice required for drug testing via development of first in vitro automated screening platform of injured mammalian brain Principal Investigator: Dr Veronique Miron, University of Edinburgh PhD Studentship
Advanced in vitro and in silico models to predict and prevent deep venous thrombosis Principal Investigator: Dr Alessio Alexiadis, University of Birmingham PhD Studentship
Developing a rapid method for identification of key proteins that define tissues to create an array of tissue-specific hydrogels for human-relevant in vitro 3D culture Principal Investigator: Professor Cathy Merry, University of Nottingham Technologies to tools grant
Refining training of non-human primates using automated home room training systems Principal Investigator: Dr Steven Kennerley, University College London Partnerships and impact awards
Transfer of the epicardial-cardiac organotypic culture model to support the ex vivo screening of gene therapy candidates Principal Investigator: Dr Paola Campagnolo, University of Surrey Partnerships and impact awards
Assessing the relevance of Galleria mellonella to antibiotic drug discovery for pulmonary infections Principal Investigator: Dr James Mason, King's College London Partnerships and impact awards
An in vivo genetic screen of lung function candidate genes using tissue specific RNAi in Drosophila melanogaster Principal Investigator: Dr Marios Georgiou, University of Nottingham PhD Studentship
Replacing the need for patient-derived xenografts and matrigel organoid culture as preclinical models for breast cancer Principal Investigator: Dr Robert Clarke, The University of Manchester Partnerships and impact awards
Utilising tissue-on-a-chip technology as an ex vivo model of breast cancer metastatic colonisation Principal Investigator: Professor John Greenman, University of Hull Partnerships and impact awards
Developing an automated apparatus for continual trials recognition memory in rodents Contractor: Dr Alex Easton, Durham University CRACK IT Solution