Using zebrafish for pre-clinical brain haemorrhage research Principal Investigator: Professor Stuart Allan, University of Manchester PhD Studentship
Reducing the use and refining the distribution of male Xenopus Principal Investigator: Professor Matthew Guille, University of Portsmouth Infrastructure grant
Building brains in a dish - using ES cells to understand brain development Principal Investigator: Dr John Mason, University of Edinburgh PhD Studentship
Improving biological integration of osseous and dermal tissues in macaque cranial implants Principal Investigator: Professor Alex Thiele, Newcastle University Strategic grant
In silico human-based methodologies for evaluation of drug cardiac safety and efficacy Principal Investigator: Professor Blanca Rodriguez, University of Oxford Infrastructure grant
Metaboderm: 3D hiPSC derived skin model and in-silico skin modelling of metabolism Contractor: Professor Lyle Armstrong, Newcells Biotech Ltd CRACK IT Challenge
InMutaGene: A human IPS cell model for gene therapy vector safety evaluation Contractor: Dr Manfred Schmidt, GeneWerk GmbH CRACK IT Challenge
A new Drosophila-based strategy to study mitochondrial transport and neuronal ageing in vivo Principal Investigator: Dr Alessio Vagnoni Fellowship
Murinised Firefly Luciferase: A new direction towards immune-shielding and biological relevance Principal Investigator: Professor James Murray, Cardiff University PhD Studentship
Development of a novel cell based bitter taste assessment assay Principal Investigator: Dr Afzal Rahman Mohammed, Aston University PhD Studentship
Comprehensive target screening by label-free cell microarray profiling to reduce animal efficacy and toxicology studies in drug discovery Contractor: Dr James Sidaway, Phenotox Ltd CRACK IT Solution
A bovine alveolus model to replace cattle in the study of host-pathogen interactions in bovine tuberculosis Principal Investigator: Professor Mark Chambers, University of Surrey Strategic grant
Microfluidic networks: an in vitro 3D culture system for the investigation of neuron-glial interactions in neurodegeneration Principal Investigator: Dr Tomas Bellamy, University of Nottingham PhD Studentship
Development and validation of a rodent touchscreen battery for assessing motivation and affective state Principal Investigator: Dr Lisa Saksida, University of Cambridge Project grant
A multi-cellular 3D model of human breast tissue to replace rodent xenograft models in breast cancer research Principal Investigator: Professor Cathy Merry, University of Nottingham Project grant
Development and characterisation of a human ex vivo model of aneurysm Principal Investigator: Dr Jason Johnson, University of Bristol PhD Studentship
Portable bioluminescence test for botulinum neurotoxin Contractor: Dr Gregory Stevens, University of Freiburg CRACK IT Solution
Affimers: animal free alternatives to antibodies Contractor: Philip Cotrel, Avacta Life Sciences CRACK IT Solution
Review of the use of two species in regulatory toxicology studies Current contact: Dr Elisa Passini Office-led project
Probing in vivo parasite biology in vitro Principal Investigator: Professor Aaron Maule, Queen's University Belfast Project grant