DM-MAP: drug and metabolite microsampling analytical platform for preclinical medicines development Principal Investigator: Dr Darragh Murnane, University of Hertfordshire PhD Studentship
Development of a non-mammalian, pre-clinical screening tool (FETOX) for predictive analysis of drug safety Principal Investigator: Dr Grant Wheeler, University of East Anglia PhD Studentship
Development of a refined model of neuropathic pain: a model without frank nerve injury Principal Investigator: Dr Andrew Dilley, University of Sussex PhD Studentship
Development of a method for non-lethal sampling from individual fish to investigate host responses to ectoparasites Principal Investigator: Professor Chris Secombes, University of Aberdeen PhD Studentship
Non-invasive real-time bioluminescence imaging in living mice to interrogate transcription factor activity and fate of engrafted stem cells Principal Investigator: Dr Tristan McKay, Manchester Metropolitan University Strategic grant
Ultrasound mediated bioluminescence tomography for high sensitivity, high spatial resolution 3D imaging Principal Investigator: Professor Stephen Morgan, University of Nottingham Strategic grant
Molecularly Imprinted Nanoparticles (MIP NPs) as non-animal antibodies substitutes for detection of viruses Principal Investigator: Dr Alessandro Poma, University College London Fellowship
Development of a patient derived cellular model of circadian disruption in bipolar disorder Principal Investigator: Dr Sridhar Vasudevan, University of Oxford PhD Studentship
QSARs Mix: Development of high accuracy QSARs for mixtures to bridge the data gaps in skin and eye irritation Contractor: Dr Paul Thomas, KREATiS CRACK IT Challenge
Contribution of autophagy to the maintenance, invasion and metastasis of melanoma stem-like sub populations. Principal Investigator: Dr David Hill, Newcastle University Fellowship
Find the target of valproic acid: pioneering the use of a non-animal model for basic biomedical (epilepsy) research Principal Investigator: Professor Robin Williams, Royal Holloway University of London PhD Studentship
Developing microfluidic systems for high throughput studies of functional neuronal networks Principal Investigator: Dr Michele Zagnoni, University of Strathclyde PhD Studentship
Reduction of use of experimental mice in type 1 diabetes research through non-invasive, in vivo longitudinal imaging Principal Investigator: Dr Maja Wallberg, University of Cambridge Project grant
DRGNET: Developing an ethical, sustainable, human sensory neuron culture model for use in therapeutic pain research Contractor: Professor Andrew Hart, NHS Greater Glasgow & Clyde CRACK IT Challenge
Labelled IMS TAG Proteins for Quantitative Mass Spectrometry Imaging Principal Investigator: Professor Malcolm Clench, Sheffield Hallam University Strategic grant
Generating zebrafish models of human eye movement disorders to replace mouse models Principal Investigator: Dr Ivana Poparic, King's College London Fellowship
Creating an in vitro model of pathogenic ossification to explore methods for dispersion Principal Investigator: Professor Liam Grover, University of Birmingham PhD Studentship
NephroTube: toxicity screening with a human renal cell line in a perfused titerplate Contractor: Northwestern Switzerland CRACK IT Challenge
VIDR: A multiscale model to minimise animal usage in Leishmaniasis drug development Contractor: Professor Paul Kaye, University of York CRACK IT Challenge
UnTangle: A microfluidics based drug-screening platform for human tau mutation neurons Contractor: Dr Selina Wray, University College London CRACK IT Challenge