Live real-time imaging of life-threatening invasive fungal infections Principal Investigator: Dr Donna MacCallum, University of Aberdeen Pilot study grant
Investigating tuberculosis by engineering human granulomas Principal Investigator: Dr Liku Tezera, University of Southampton Pilot study grant
Development of computational models of bone formation and resorption to predict changes in bone in preclinical intervention studies Principal Investigator: Dr Ilaria Bellantuono, University of Sheffield Project grant
Assessing cumulative severity in macaques used in neuroscience research Principal Investigator: Professor Melissa Bateson, Newcastle University Project grant
Imprecision and importance: Probabilistic graphical models in toxicology Principal Investigator: Dr Jonathan Pitchford, University of York Strategic grant
Quantifying the behavioural and facial correlates of pain in laboratory macaques Principal Investigator: Dr Sarah-Jane Vick, University of Stirling Project grant
Uncertainty and confidence in applying mathematical models and in vitro data in toxicological safety assessments Principal Investigator: Dr John Gosling, University of Leeds Strategic grant
An integrated platform to assay melanoblast and melanoma invasion of epidermis in vitro Principal Investigator: Dr Richard Mort, University of Edinburgh PhD Studentship
Structural identifiability and indistinguishability analysis as tools for quantitative and systems pharmacology to support the 3Rs Principal Investigator: Dr Michael Chappell, University of Warwick Strategic grant
Human pluripotent stem cell cardiomyocytes and hepatocytes with engineered genotypes for drug safety evaluation Principal Investigator: Professor Chris Denning, University of Nottingham Project grant
Validating reward-related behaviour for welfare assessment, and improving welfare through increased predictability of events Principal Investigator: Professor Hannah Buchanan-Smith, University of Stirling Project grant
Establishment of consensual husbandry protocols for laboratory Xenopus laevis using novel physiological and behavioural techniques Principal Investigator: Dr Charlotte Hosie, University of Chester Project grant
Prediction of human cardiotoxic QT prolongation using in vitro multiple ion channel data and mathematical models of cardiac myocytes Principal Investigator: Dr Gary Mirams, University of Oxford Strategic grant
Developing an in vitro approach to study transmission of respiratory viruses Principal Investigator: Professor Wendy Barclay, Imperial College London Project grant
Individually customisable, non-invasive head immobilisation for primates with the option for voluntary engagement Principal Investigator: Professor Christopher Petkov, Newcastle University Pilot study grant
Development and validation of an automated test of animal affect and welfare for laboratory rodents Principal Investigator: Professor Michael Mendl, University of Bristol Project grant
Use of PrP transgenic Drosophila to measure mammalian prion infectivity Principal Investigator: Dr Raymond Bujdoso, University of Cambridge Project grant
eGUT: a Tool for Predictive Computer Simulation of the Gut Microbiota and Host Interactions Principal Investigator: Dr Jan-Ulrich Kreft, University of Birmingham Project grant
Improving the principles of the 3Rs through new integrative metabolomic and gene expression resources for signalling studies in burn injuries Principal Investigator: Dr Istvan Nagy, Imperial College London PhD Studentship
Refining the study of fatigue in mouse models of chronic liver disease Principal Investigator: Dr Claire Richardson, Newcastle University Fellowship