CRANNME: The complete removal of animal use for neuromuscular effectors testing Principal Investigator: Professor Mark Lewis, Loughborough University Pilot study grant
Non-invasive imaging to reduce and refine the use of animals and monitor their welfare during the course of experimentations in oncology Principal Investigator: Dr Francois Lassailly, Cancer Research UK Pilot study grant
In vitro methods for replacement of current in vivo assays for development of drugs against heterogeneous cancer stem cell populations Principal Investigator: Dr Adrian Biddle, Queen Mary University of London Fellowship
The role of bronchoconstriction in the development of airway remodelling and its effects upon lung function Principal Investigator: Dr Amanda Tatler, University of Nottingham Fellowship
Investigation of behavioural and physiological responses to fin-clipping in zebrafish Principal Investigator: Ms Gidona Goodman, University of Edinburgh Pilot study grant
Optimising liver equivalents to model liver fibrosis Principal Investigator: Dr Fiona Oakley, Newcastle University Pilot study grant
The detection, assessment and alleviation of pain in laboratory zebrafish Principal Investigator: Dr Lynne Sneddon, University of Liverpool Project grant
Combinatorial mathematical modelling & novel toxicological profiling of drug-induced hepatotoxicity Principal Investigator: Dr John Ward, Loughborough University PhD Studentship
Developing a novel model to assess the specificity of appetite-reducing agents Principal Investigator: Dr Kevin Murphy, Imperial College London PhD Studentship
Feasibility of replacing invasive heart pressure measurements with non-invasive MR Elastography to reduce rodent numbers in pre-clinical research Principal Investigator: Dr Jurgen Schneider, University of Oxford Pilot study grant
Assessing welfare in fish: the answer is in the water! Principal Investigator: Dr Ioanna Katsiadaki, Centre for Environment Fisheries and Aquaculture Science Project grant
Human and mouse artificial lymph nodes: novel technology to reduce and replace the use of animal models in clinical and developmental immunology Principal Investigator: Dr Mark Coles, University of York Project grant
Refinement of the use of fluid control as a motivational tool for non-human primates in neuroscience research Principal Investigator: Professor Alex Thiele, Newcastle University PhD Studentship
The development of an in vitro model of spinal cord injury to study aligned neurite outgrowth Principal Investigator: Professor Susan Barnett, University of Glasgow PhD Studentship
Characterisation and validation of an organotypic slice culture model of Alzheimer’s disease Principal Investigator: Dr Wendy Noble, King's College London PhD Studentship
Development of a non-animal model for characterizing drug-resistant tumours Principal Investigator: Professor Catherine Pears, University of Oxford PhD Studentship
A Drosophila model of Candida albicans gastrointestinal infection Principal Investigator: Professor Petros Ligoxygakis, University of Oxford PhD Studentship
Bone healing and regeneration in an ex vivo bioreactor – evaluation of angiogenesis and reparation for clinical application Principal Investigator: Professor Richard Oreffo, University of Southampton PhD Studentship
In vitro and in silico models of gut bacterial diversity and its impacts on human health Principal Investigator: Professor Timothy Barraclough, Imperial College London PhD Studentship
Development of non-radioactive labels for a receptor binding assay for paralytic shellfish poisoning (PSP) toxin testing Principal Investigator: Professor Christopher Elliott, Queen's University Belfast PhD Studentship