Development of a sensitive in vitro system for anti-alpha-synuclein aggregation drug screening Principal Investigator: Dr Maria Eugenia Herva Moyano, University of Cambridge Fellowship
Single-cell analysis of replicative fate in vivo by heavy water labelling of DNA and mass spectrometry Principal Investigator: Dr Michelle Oyen, University of Cambridge PhD Studentship
Dictyostelium as non-animal model to identify DNA repair pathways as targets for cancer therapy Principal Investigator: Dr Nicholas Lakin, University of Oxford PhD Studentship
Recapitulating the adult stem cell and cancer stem cell niche in vitro using 3D engineered matrices Principal Investigator: Professor Christine Watson, University of Cambridge PhD Studentship
A disease model to investigate vascular endothelial function for genetic stroke CADASIL Principal Investigator: Dr Tao Wang, University of Manchester PhD Studentship
Development of an in vitro culture system generating haematopoietic dendritic cells (DCs) from mouse embryonic stem cells Principal Investigator: Dr Pierre Guermonprez, King's College London PhD Studentship
Development of urinary exosomes as biomarkers of drug-induced kidney injury Principal Investigator: Dr James Dear, University of Edinburgh PhD Studentship
Refining an established model of hypertension in the mouse Principal Investigator: Professor Susan Brain, King's College London PhD Studentship
Development of an in vitro system to determine the causes of aberrant, leukaemogenic V(D)J recombination reactions Principal Investigator: Dr Joan Boyes, University of Leeds PhD Studentship
Using molecular simulation to improve prediction of drug export Principal Investigator: Dr Philip Biggin, University of Oxford PhD Studentship
SyRF: the CAMARADES/NC3Rs in vivo systematic review and meta-analysis facility Principal Investigator: Professor Malcolm Macleod, University of Edinburgh Infrastructure grant
Training and teaching resources to underpin implementation of refinement of in vivo studies Principal Investigator: Professor Paul Flecknell, Newcastle University Infrastructure grant
Reducing the number of non-human primates in research by developing a rodent model of selective attention Principal Investigator: Dr Samuel Solomon, University College London Pilot study grant
Finding effective analgesics in zebrafish by analysing effects on the nervous system (CNS) Principal Investigator: Professor Catherina Becker, University of Edinburgh Pilot study grant
Live imaging of mucosal and vascular inflammation in zebrafish in response to a high cholesterol diet Principal Investigator: Professor Margaret Dallman, Imperial College London PhD Studentship
Rodent Little Brother: A Brave New Homecage Contractor: Professor Douglas Armstrong, Actual Analytics Ltd CRACK IT Challenge
Using C. elegans to produce proteins from parasitic nematodes for research and therapeutic use Principal Investigator: Dr David Weinkove, Durham University Pilot study grant
Signalling pathways of leukocyte migration in silico Principal Investigator: Dr Juliane Liepe, Imperial College London Fellowship
An early screen for emetic liability of NCEs using the amoeba Dictyostelium Contractor: Professor Robin Williams, Royal Holloway CRACK IT Solution
PREDART: An integrative Dictyostelium, C. elegans and zebrafish approach to assess DART Contractor: Professor Raymond Peters, University of Utrecht CRACK IT Challenge