Use of Drosophila models to explore the function of asthma susceptibility genes Principal Investigator: Professor Donna Davies, University of Southampton Strategic grant
Developing a model for the study of respiratory inflammation in the zebrafish Principal Investigator: Professor Margaret Dallman, Imperial College London Strategic grant
Implanted optical imaging laboratories for deep-tissue in vivo imaging Principal Investigator: Professor Andrew Harvey, University of Glasgow Strategic grant
Novel biomarker platform for a 3Rs approach to assessment of developmental and reproductive toxicity Principal Investigator: Dr Catherine Pears, University of Oxford Project grant
Developing a non-animal model system to investigate bitter tastants as new treatments for asthma Principal Investigator: Professor Robin Williams, Royal Holloway University of London Strategic grant
The Drosophila adult intestine as a model for radiation tolerance and resistance Principal Investigator: Dr Joaquin de Navascues, Cardiff University Pilot study grant
Inhalation Translation: Differentiating alveolar macrophage responses to inhaled medicines Contractor: Dr Ben Forbes, Kings College London CRACK IT Challenge
Development of novel imaging agents for the prospective quantification of joint damage to reduce animal numbers in osteoarthritis research Principal Investigator: Professor Tonia Vincent, University of Oxford Project grant
Refining the mouse model of footpad immunisation and infection Principal Investigator: Dr Owain Millington, University of Strathclyde Pilot study grant
Mechanisms of intestinal epithelial responses to inflammatory modulators Principal Investigator: Professor Inke Nathke, University of Dundee Project grant
Development of human ex vivo bone-tumour niche for the study of cancer bone disease Principal Investigator: Dr James Edwards, University of Oxford Pilot study grant
Real-time monitoring techniques and simplistic platelet assays to reduce and refine animal use in cardiovascular and respiratory biomedical research Principal Investigator: Dr Michael Emerson, Imperial College London Project grant
Motor neuron regeneration in larval zebrafish Principal Investigator: Professor Catherina Becker, University of Edinburgh PhD Studentship
Exploitation of an ex vivo disease model to characterise early events in retinal degeneration Principal Investigator: Dr J. Arjuna Ratnayaka, University of Southampton PhD Studentship
Targeted, radiolabelled near-infrared quantum dots for high sensitivity and resolution, dual modality imaging of human tumours in mice Principal Investigator: Dr Anna Grabowska, University of Nottingham Strategic grant
Determining the source of variability within experimental stroke models Principal Investigator: Dr Claire Gibson, University of Leicester Pilot study grant
A novel product for reducing animal numbers in the production of transgenic mice Contractor: Dr Nadia Gopichandran, Ostara Biomedical Ltd CRACK IT Solution
Developing molecular therapies for glaucoma using an ex vivo human organ culture system Principal Investigator: Professor Colin Willoughby, University of Liverpool PhD Studentship
Towards engineering a multi-cell lineage multi-organism intestine Principal Investigator: Dr Marc Veldhoen, Babraham Institute Cambridge PhD Studentship
3D gene knockout tissue models using adult human stem cells Principal Investigator: Professor Paul Genever, University of York PhD Studentship