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Activity type

Topic

Model

Impact stories

677 results

A Drosophila model of Candida albicans gastrointestinal infection

Principal Investigator: Professor Petros Ligoxygakis, University of Oxford

PhD Studentship

Bone healing and regeneration in an ex vivo bioreactor – evaluation of angiogenesis and reparation for clinical application

Principal Investigator: Professor Richard Oreffo, University of Southampton

PhD Studentship

A stock image of round glass dishes containing blue and green liquid arranged closely together.

In vitro and in silico models of gut bacterial diversity and its impacts on human health

Principal Investigator: Professor Timothy Barraclough, Imperial College London

PhD Studentship

Development of non-radioactive labels for a receptor binding assay for paralytic shellfish poisoning (PSP) toxin testing

Principal Investigator: Professor Christopher Elliott, Queen's University Belfast

PhD Studentship

RETINAS: Origin retinas syringe insertion device

Contractor: Allen Pearson, Origin Product Design Limited

CRACK IT Challenge

Optimisation of a flow-based human in vitro blood–brain barrier model to replace animal models for studying immunopathogenesis of viral brain infections

Principal Investigator: Dr Adjanie Patabendige, University of Liverpool

Fellowship

Reducing animal dependency in diabetes research through pancreatic stem cells

Principal Investigator: Professor Mark Dunne, University of Manchester

PhD Studentship

Construction of a miniaturised human lymph node model as an alternative to the Local Lymph Node Assay

Principal Investigator: Professor Amir Ghaemmaghami, University of Nottingham

PhD Studentship

The arm of a researcher can be seen pipetting red liquid into multi-well plates

Reduction & refinement in animal models of neuropathic pain: using systematic review & meta-analysis

Principal Investigator: Dr Emily Sena, University of Edinburgh

Project grant

Using induced pluripotent stem cells as a replacement for in vivo models to screen novel therapies which target self-renewal pathways in chronic myeloid leukaemia

Principal Investigator: Dr Helen Wheadon, University of Glasgow

PhD Studentship

Refining, reducing and replacing in vivo WHO-standard preclinical assays of snake venom pathology and antivenom efficacy

Principal Investigator: Dr Robert Harrison, Liverpool School of Tropical Medicine

PhD Studentship

Developing an integrated "in vitro carcinogenicity predictive tool" utilising in vitro cell signalling and cell behaviour assessment coupled with in vitro genotoxicity data

Principal Investigator: Professor Gareth Jenkins, Swansea University

Strategic grant

Wireless high-bandwidth trans-cutaneous signal transmission

Principal Investigator: Professor Stuart Baker, Newcastle University

Project grant

Development of human epithelial cell transformation models for carcinogen screening, employing defined phenotypic endpoints mechanistically representative of rate-limiting events in human carcinogenesis

Principal Investigator: Professor Robert Newbold, Brunel University

Strategic grant

The use of gene expression profiles to predict protective immunity without the need for disease challenge

Principal Investigator: Dr Roland Ashford, Veterinary Laboratories Agency

Pilot study grant

An advanced model for neurodegeneration studies in the fruit fly Drosophila melanogaster

Principal Investigator: Dr Ezio Rosato, University of Leicester

Project grant

Replacement of animal models for tumour biology with a multifunctional microfluidic-based approach

Principal Investigator: Professor John Greenman, University of Hull

Project grant

A fully-automated system for positive reinforcement training of group-housed non-human primates

Principal Investigator: Dr Andrew Jackson, Newcastle University

Pilot study grant

The assessment of pain using facial expressions in laboratory mice, rats, rabbits and macaques

Principal Investigator: Dr Matt Leach, Newcastle University

Project grant

Cognition: A miniature wireless EEG system for continuous monitoring of mice brainwave activity

Contractor: Professor Esther Rodriguez-Villegas, Imperial College London

CRACK IT Challenge