Targeted protein degradation as a novel approach to study protein function in human platelets Principal Investigator: Professor Ingeborg Hers, University of Bristol PhD Studentship
A novel in vitro reporter system for blood stem cell activity Principal Investigator: Professor David Kent, University of York PhD Studentship
Refining the tagging of wild fish and sharks Principal Investigator: Dr Matthew Witt, University of Exeter PhD Studentship
Understanding how altered brain metabolism causes mitochondrial disease Principal Investigator: Dr Joseph Bateman, King's College London PhD Studentship
Combining a fully synthetic hydrogel with human intestinal organoids to model pathological matrix remodelling in Inflammatory Bowel Disease Principal Investigator: Professor Eileen Gentleman, King's College London PhD Studentship
3D bioprinted microtissues to develop patient-specific non-animal technologies (NAT) in cancer drug development Principal Investigator: Dr Deepali Pal, Northumbria University PhD Studentship
Insects as models to study wound healing, infection and the wound microbiome Principal Investigator: Dr Ronan McCarthy, Brunel University PhD Studentship
A 3Rs approach to investigate the feto-maternal interface: visualisation of pathogen and antibody in a 3D in vitro human placental model Principal Investigator: Professor Aras Kadioglu, University of Liverpool PhD Studentship
Development and validation of 3D in vitro dormant myeloma cell models to reduce and replace animal studies Principal Investigator: Dr Michelle Lawson, University of Sheffield PhD Studentship
Live monitoring of foreign-body response in animals by diffuse Raman spectroscopy Principal Investigator: Professor Ioan Notingher, University of Nottingham Project grant
Development of a New Human Model of Lung Squamous Cell Carcinoma Progression Principal Investigator: Dr Carlos Lopez-Garcia, University of Manchester Project grant
Establishing the novel ex-vivo focal demyelination model of Multiple Sclerosis in other laboratories to reduce and replace live animal use Principal Investigator: Dr Ben Newland, Cardiff University Partnerships and impact awards
Adoption of a mouse model of veterinary filariasis for preclinical drug testing Principal Investigator: Dr Joseph Turner, Liverpool School of Tropical Medicine Partnerships and impact awards
A novel Drosophila model of chronic inflammatory lung disease to explore airway damage, inflammation and infection in vivo Principal Investigator: Dr Helen Weavers, University of Bristol PhD Studentship
Determining the efficacy and safety of cancer chemotherapeutics for cholangiocarcinoma (CCA) using Human Precision Cut Tissue Slices (hPCTS) Principal Investigator: Dr Laura Randle, Unviversity of Liverpool Partnerships and impact awards
Using a novel, high welfare in vivo feeding device for poultry red mite and its integration with other novel tools for this parasite Principal Investigator: Dr Alasdair Nisbet, Moredun Research Institute Partnerships and impact awards
Go North: Expanding the use of the chick embryo model in cancer research to a multiuser facility at the University of Strathclyde Principal Investigator: Dr Marie Boyd, University of Strathclyde Partnerships and impact awards
A non-protected larval zebrafish model for the investigation of novel strategies to protect against nerve agent-induced toxicity and seizures Principal Investigator: Dr Matthew Parker, University of Portsmouth Partnerships and impact awards
Review of animal use requirements in WHO biologics guidelines Current contact: Dr Elliot Lilley Office-led project
Acquisition of the Drosophila model system to understand mechanisms of innate immunity regulation by chromatin dynamics Principal Investigator: Dr Patrick Varga-Weisz, University of Essex Partnerships and impact awards